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Keap1-Nrf2 Pathway and Autophagy The selective autophagy substrate p62 contains an ETGE-like motif, STGE, which could be phosphorylated by mTOR complex 1 to bind to Keap1 with higher affinity (Taguchi et al., 2012)

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In the rat acute lung injury model, Tanshinone IIA inhibited inflammation and oxidative stress, reduced glycocalyx degradation, and improved lung function [124]

72 Although the mechanism remains unclear, regular physical activity is regarded as a protective factor of breast cancer incidence